Holman-Miller Sign

  • The Holman-Miller Sign is a radiographic sign characterized by anterior bowing of the posterior maxillary wall due to a space occupying lesion in the pterygopalatine fossa (PPF).1
  • It is often described as a pathognomonic feature with a Juvenile Nasal Angiofibroma (JNA).

Holman Miller Sign in Juvenile Nasal Angiofibroma

  1. Holman CB and Miller WE. Juvenile nasopharyngeal fibroma: roentgenologic characteristics. American Journal of Roentgenol. Rad. Therapy & Nuclear Med 1965;94:292-298. 

Last updated October 10, 2022