Frey’s Syndrome

  • Frey’s syndrome, also known as auriculotemporal syndrome or gustatory sweating, is a phenomenon where a patient develops sweating while eating following facial nerve injury.1
    • This is thought to be due to abnormal reinnervation of cholinergic skin sweat glands (which typically have sympathetic innervation) with parasympathetic fibres which control salivation.
    • Frey’s Syndrome most commonly occurs in the context of parotidectomy or traumatic parotid injury.
  • Compare this with Bogorad Syndrome (aka. crocodile tear syndrome), which causes lacrimation while eating.
  1. De Bree, Remco, Isaäc Van Der Waal, and C. René Leemans. “Management of Frey syndrome.” Head & Neck: Journal for the Sciences and Specialties of the Head and Neck 29.8 (2007): 773-778. 

Last updated October 06, 2022